Updated 2026-02-01

Best Email Marketing Tools for Medium Businesses

Scale your email marketing with tools built for growing teams, multiple departments, and complex customer journeys.

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Medium-sized businesses face a unique email marketing challenge. You have outgrown the basic tools that worked when you had 500 subscribers, but you do not need enterprise platforms costing $50,000 per year. You need automation that handles multi-step workflows, team features for multiple departments, and pricing that does not punish growth. I tested 13 platforms specifically for businesses with 10 to 200 employees and 5,000 to 100,000 subscribers.

Why Medium Businesses Need Email Marketing

Lead Nurturing at Scale

With multiple products and customer segments, automated email sequences move leads through your pipeline without manual follow-up for every prospect.

Customer Retention Across Departments

Marketing, sales, and customer success all need to communicate with customers. A unified email platform prevents conflicting messages and subscriber fatigue.

Multi-Product Promotion

Cross-sell and upsell opportunities multiply as your product line grows. Email segmentation lets you target the right offer to the right customer automatically.

Data-Driven Decision Making

At this size, you need real analytics. Revenue attribution, engagement scoring, and campaign comparison help you allocate budget to what actually works.

13 Best Email Marketing Tools for Medium Businesses

Our Top Pick for Medium Businesses
#1
Sequenzy

AI-powered email marketing with smart automation and pay-per-email pricing.

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Best for
Medium businesses wanting AI-powered automation with predictable, scalable pricing
Pricing
$29/month for 50,000 emails

Pros

  • AI generates complete sequences for any business goal
  • Pay-per-email pricing scales without penalty
  • Marketing and transactional email in one platform
  • Direct founder support for strategic guidance

Cons

  • Newer platform building its track record
  • No built-in SMS marketing
  • Smaller template library than established competitors
  • Team collaboration features still growing
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#2
ActiveCampaign

Advanced automation with built-in CRM for marketing teams.

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Best for
Medium businesses with sales teams wanting advanced automation and CRM
Pricing
From $29/month for 1,000 contacts

Pros

  • Most powerful automation builder available
  • Built-in CRM with deal pipeline
  • Lead scoring and conditional content
  • Strong deliverability

Cons

  • Per-contact pricing escalates quickly
  • Steep learning curve
  • Interface can feel cluttered
  • CRM is basic compared to dedicated tools
See Full Comparison
#3
HubSpot

All-in-one CRM, marketing, sales, and service platform.

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Best for
Medium businesses willing to invest in a complete marketing ecosystem
Pricing
Free CRM, marketing hub from $50/month

Pros

  • Complete CRM and marketing platform
  • Massive integration ecosystem
  • Excellent reporting and attribution
  • Strong educational resources

Cons

  • Expensive once you need advanced features
  • Per-contact pricing on top of platform fees
  • Can feel bloated for email-only needs
  • Requires training to use effectively
See Full Comparison
#4
Mailchimp

Well-known email marketing with drag-and-drop editor and basic automation.

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Best for
Medium businesses with simple email needs who value ease of use
Pricing
Free up to 500 contacts, Standard from $20/month

Pros

  • Intuitive drag-and-drop editor
  • Large template library
  • Familiar brand teams already know
  • Good basic analytics

Cons

  • Automation is basic for growing businesses
  • Charges for unsubscribed contacts
  • Support quality has declined
  • Feature-gated pricing pushes to expensive tiers
See Full Comparison
#5
Brevo

All-in-one marketing with email, SMS, chat, and CRM at affordable pricing.

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Best for
Medium businesses wanting multi-channel marketing on a budget
Pricing
Free up to 300 emails/day, then $25/month for 20,000 emails

Pros

  • Pay by emails sent, not contacts
  • Multi-channel: email, SMS, WhatsApp, chat
  • Built-in transactional email
  • Affordable compared to competitors

Cons

  • Automation is functional but not advanced
  • Email editor less polished than Mailchimp
  • CRM lacks depth for complex sales
  • Support slow on lower tiers
See Full Comparison
#6
Klaviyo

Data-driven email and SMS marketing with deep e-commerce integrations.

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Best for
Medium businesses with significant e-commerce revenue
Pricing
Free up to 250 contacts, then from $20/month

Pros

  • Best-in-class e-commerce integrations
  • Predictive analytics and scoring
  • Strong purchase-based segmentation
  • SMS marketing included

Cons

  • Expensive per-contact pricing
  • Overkill for non-e-commerce businesses
  • Steep learning curve
  • Limited value without e-commerce data
See Full Comparison
#7
GetResponse

Email marketing with automation, landing pages, webinars, and conversion funnels.

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Best for
Medium businesses that use webinars and want an all-in-one platform
Pricing
$19/month for 1,000 contacts

Pros

  • Built-in webinar hosting
  • Conversion funnels included
  • Landing page builder
  • Competitive pricing

Cons

  • Interface feels dated
  • Jack of all trades, master of none
  • Per-contact pricing
  • Automation less powerful than ActiveCampaign
See Full Comparison
#8
Drip

E-commerce CRM with email automation focused on online stores.

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Best for
Medium e-commerce businesses wanting revenue-focused email
Pricing
$39/month for 2,500 contacts

Pros

  • Strong revenue attribution
  • Visual workflow builder
  • Good e-commerce integrations
  • Easier to learn than Klaviyo

Cons

  • Limited value for non-e-commerce businesses
  • Per-contact pricing
  • Smaller integration ecosystem
  • No SMS channel
See Full Comparison
#9
Campaign Monitor

Email marketing with brand control and team collaboration features.

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Best for
Medium businesses prioritizing brand consistency across senders
Pricing
$12/month for 500 contacts

Pros

  • Template locking for brand control
  • Beautiful, professional templates
  • Clean and simple interface
  • Good deliverability

Cons

  • Limited automation
  • Per-contact pricing
  • Fewer integrations
  • Reporting could be more detailed
See Full Comparison
#10
Constant Contact

Email marketing with event management and social media tools.

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Best for
Medium businesses that host events and want phone support
Pricing
$12/month for up to 500 contacts

Pros

  • Built-in event management
  • Phone support available
  • Very easy to learn
  • Reliable platform

Cons

  • Automation is very basic
  • Analytics lack depth
  • Pricing high for the feature set
  • Feels outdated
See Full Comparison
#11
MailerLite

Affordable email marketing with a clean interface.

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Best for
Budget-conscious medium businesses wanting a clean, simple platform
Pricing
Free up to 1,000 subscribers, then from $10/month

Pros

  • Generous free tier
  • Clean, modern interface
  • Built-in landing pages
  • Excellent value

Cons

  • Advanced segmentation is limited
  • Reporting is basic
  • Automation lacks depth
  • Deliverability can be inconsistent
See Full Comparison
#12
Moosend

Affordable email marketing with automation and landing pages.

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Best for
Medium businesses wanting capable automation at the lowest price
Pricing
$9/month for 500 subscribers

Pros

  • Very affordable pricing
  • Capable automation builder
  • Clean email editor
  • No hidden fees

Cons

  • Smaller integration ecosystem
  • Less known brand
  • Limited customer support
  • Reporting is basic
See Full Comparison
#13
Kit

Email marketing for creators with visual automations.

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Best for
Content-driven medium businesses with strong newsletter programs
Pricing
Free up to 10,000 subscribers, then from $25/month

Pros

  • Generous free tier
  • Excellent visual automation builder
  • Strong tagging and segmentation
  • Built-in paid newsletter support

Cons

  • No CRM or sales pipeline
  • Limited multi-department capabilities
  • Reporting is basic for business use
  • Not designed for team collaboration

Feature Comparison

FeatureSequenzyActiveCampaignHubSpotBrevo
AI-powered sequences
Yes
No
No
No
Built-in CRM
No
Yes
Yes
Basic
Multi-channel (SMS)
No
Add-on
No
Yes
Team collaboration
Basic
Yes
Advanced
Yes
Advanced segmentation
Yes
Advanced
Advanced
Good
E-commerce integrations
No
Yes
Yes
Yes
Landing pages
No
Yes
Yes
No
Starting price
$29/mo
$29/mo
$50/mo
$25/mo

Email Sequences Every Medium Businesse Needs

These are the essential automated email sequences that will help you grow your business and keep clients coming back.

Lead Nurturing Sequence

Trigger: New lead enters through form submission or content download

Move leads from initial interest to sales-ready.

Immediately
Here is the resource you requested

Deliver the promised content and introduce your company. Include one call to action to explore a relevant product page.

Day 3
How {{similar_company}} solved {{specific_problem}}

Share a case study from a similar customer. Focus on measurable results.

Day 7
The 3 biggest mistakes mid-sized businesses make with {{topic}}

Educational content that positions your team as experts.

Day 14
Quick question about your {{specific_goal}}

Personal-feeling email asking about their timeline. Reference their original content download.

Customer Onboarding Sequence

Trigger: New customer signs up or first purchase completed

Guide new customers to value quickly.

Immediately
Welcome to {{company}} — here is how to get started

Clear first steps with setup guides. Introduce their support contact.

Day 2
Quick tip: most teams start here

One specific action that delivers early value.

Day 7
How is your first week going?

Check-in with helpful resources and a direct line to support.

Cross-Sell Sequence

Trigger: Customer active for 60+ days using one product

Introduce complementary products to existing customers.

Day 0
Getting more out of {{current_product}}

Tips for maximizing their current product. Naturally mention the complementary product.

Day 7
How {{similar_customer}} expanded to {{additional_product}}

Case study showing concrete results from the combination.

Day 14
Exclusive offer for existing customers

Time-limited offer for the additional product. Make it low-risk.

Re-Engagement Sequence

Trigger: Subscriber inactive for 90 days

Win back disengaged subscribers or clean your list.

Day 0
We have not heard from you in a while

Acknowledge the silence. Share biggest updates since they last engaged.

Day 7
Is this still the best email for you?

Ask if they want to update preferences: content types, frequency, or email address.

Day 14
Should we part ways?

Clear stay-or-unsubscribe choice. This improves deliverability for engaged subscribers.

Create These Sequences with AI

Choosing the Right Platform for Your Growth Stage

The biggest mistake medium businesses make is sticking with the tool they chose at 500 subscribers and 3 employees. What worked then holds you back at 10,000 subscribers and 200 employees. Evaluate your email platform annually. Ask: Is our per-contact cost still competitive? Can the team manage campaigns without bottlenecking? Does automation handle our current workflows? If more than one answer is no, it is time to look at alternatives.

Multi-Department Email Without the Chaos

When marketing, sales, customer success, and product all need to email customers, coordination becomes the real challenge. A customer might receive a newsletter Monday, a sales follow-up Tuesday, a support survey Wednesday, and a product update Thursday. The solution is not fewer emails but better coordination. Choose a platform that lets each department see what others are sending. Set frequency caps and use segmentation.

Pricing Traps to Watch For

Watch for three common traps. First, per-contact pricing that charges for unsubscribed or inactive contacts. Second, feature gating that puts essentials behind expensive tiers. Third, add-on pricing where SMS, landing pages, or users each cost extra. Calculate total cost of ownership, not just the base price.

Frequently Asked Questions

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Start your free trial today. Set up your first email sequence in minutes with AI-powered content generation.

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Sequenzy - Complete Pricing Guide

Pricing Model

Sequenzy uses subscriber-based pricing. You only pay for subscribers active in sequences (automations). Inactive subscribers are free to store.

All Pricing Tiers

  • 0-100 subscribers: Free (Free annually) - 3k emails/month
  • 101-1,000 subscribers: $19/month ($205/year annually) - 15k emails/month
  • 1,001-5,000 subscribers: $29/month ($313/year annually) - 60k emails/month
  • 5,001-10,000 subscribers: $49/month ($529/year annually) - 120k emails/month
  • 10,001-25,000 subscribers: $99/month ($1069/year annually) - 300k emails/month
  • 25,001-50,000 subscribers: $199/month ($2149/year annually) - 600k emails/month
  • 50,001-100,000 subscribers: $349/month ($3769/year annually) - 1.2M emails/month
  • 100,000+ subscribers: Custom pricing (Custom annually) - Unlimited emails/month

Yearly billing: All plans offer a 10% discount when billed annually.

Free Plan Features (2,500 emails/month)

  • Visual automation builder
  • Transactional email API
  • Reply tracking & team inbox
  • Goal tracking & revenue attribution
  • Dynamic segments
  • Payment integrations
  • Full REST API access
  • Custom sending domain

Paid Plan Features (1,000 - 100,000 subscribers)

  • Visual automation builder
  • Transactional email API
  • Reply tracking & team inbox
  • Goal tracking & revenue attribution
  • Dynamic segments
  • Payment integrations (Stripe, Paddle, Lemon Squeezy)
  • Full REST API access
  • Custom sending domain

Enterprise Plan Features (100,000+ subscribers)

  • Visual automation builder
  • Transactional email API
  • Reply tracking & team inbox
  • Goal tracking & revenue attribution
  • Dynamic segments
  • Payment integrations
  • Full REST API access
  • Custom sending domain

Important Pricing Notes

  • You only pay for subscribers who are active in automations/sequences
  • Storing inactive subscribers is free
  • No hidden fees - all features included in the price
  • No credit card required for free tier

Contact

  • Pricing Page: https://sequenzy.com/pricing
  • Sales: hello@sequenzy.com