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B2B Email Sequence Templates: Sales, Nurture, and Follow-up Sequences

16 min read

B2B email sequences are different from consumer emails. Your buyers have longer decision cycles, multiple stakeholders, and larger budgets. They're evaluating you against alternatives and need to justify the purchase internally. Generic email templates won't cut it.

This guide provides B2B-specific email sequences for the most common scenarios: cold outreach, lead nurturing, demo follow-ups, and proposal follow-ups. Each template is designed for the longer, more complex B2B buying process.

What Makes B2B Email Different

B2B email sequences need to account for several realities that don't apply to consumer marketing:

B2B RealityImplication for Email
Multiple stakeholdersProvide shareable content and talking points
Longer sales cyclesMore touchpoints, patience required
Higher stakes decisionsMore emphasis on risk reduction and proof
Research-heavy buyersEducational content, not just sales pitches
Budget approval processesROI-focused messaging and business cases

The core principle: B2B buyers need to feel confident they're making the right decision and be able to defend that decision to others. Your emails should help them build that confidence.

Sales Outreach Sequences

Cold outreach in B2B requires patience and persistence. Most responses come from emails 3-5, not email 1. The sequence should provide value at every step, not just ask for meetings.

The 7-Email B2B Outreach Sequence

Day 0

First contact with a prospect

Subject Line

[Specific observation about their company]

Email Body

Hi [firstName],

I noticed [Their Company] recently [trigger event: new hire, funding, product launch, expansion]. Congrats on the momentum.

When companies hit this stage, they often run into [specific pain point your product solves]. We've helped companies like [Similar Company] address this by [brief solution description], resulting in [specific result].

I'm not sure if this is relevant for [Their Company], but if you're thinking about [pain point], I'd love to share what's working for others in [their industry].

Would a quick 15-minute call make sense?

[Your Name] [Title], [Company]

Outreach Sequence Timing

EmailDayPurpose
Initial outreach0Open the conversation
Value add3Prove you're helpful
Social proof7Build credibility
Different angle10Find the real priority
Quick check-in14Maintain visibility
Last value21Final value delivery
Breakup28Prompt a response

Key insight: The breakup email often gets the highest response rate. Something about explicitly saying you'll stop reaching out prompts people to reply.

For more cold outreach strategies, see our cold email sequence guide.

Lead Nurture Sequences

Not every lead is ready to buy. Lead nurture sequences keep you top of mind with prospects who have shown interest but aren't ready for a sales conversation yet. These are typically triggered by content downloads, webinar attendance, or newsletter signups.

Content-Based Nurture Sequence

Instant

Immediately after content download

Subject Line

Your [resource name] is ready

Email Body

Hi [firstName],

Here's the [Resource Name] you requested: [Download link]

Before you dive in, here's the key insight from section 3 that most readers find most actionable:

[One-line summary of key insight]

Companies that implement this typically see [specific result]. Worth focusing on first.

Over the next few weeks, I'll share some related content that builds on what's in this guide. If you have questions about anything in there, just reply.

[Your Name]

P.S. If you'd rather skip ahead and talk to someone about how this applies to [Their Company], you can book time here: [Calendar link]

Nurture Sequence Best Practices

Timing: Space emails 3-7 days apart. Too frequent feels pushy. Too sparse loses momentum.

Content mix: Balance educational content (70%) with product-focused content (30%). You want to be seen as a helpful resource, not just a vendor pushing for a sale.

Personalization: Reference their company, industry, or specific actions they've taken. Generic nurture emails get ignored.

For more nurture strategies, see our email nurture sequence examples.

Demo Follow-up Sequences

After someone attends a demo, the sale isn't closed. They need to evaluate, get internal buy-in, and compare alternatives. Your follow-up sequence should support this process.

Post-Demo Follow-up Sequence

Within 2 hours of demo

Same day as demo

Subject Line

Thanks for the demo + resources

Email Body

Hi [firstName],

Thanks for taking the time to see [Product] today. Great questions about [specific topic they asked about].

As promised, here's what we discussed:

Recording: [If recorded, link here]

Key resources:

  • [Resource addressing their main concern]
  • [Case study from similar company]
  • [Pricing/proposal if requested]

Next steps we discussed:

  1. [Action item 1]
  2. [Action item 2]

I'll follow up [specific day] to see how the evaluation is going. In the meantime, reply if any questions come up.

[Your Name]

Demo Follow-up Timing

EmailTimingGoal
Immediate follow-upSame dayReinforce key points, provide resources
Internal champion supportDay 2Arm them for internal conversations
Objection handlerDay 5Address concerns proactively
Progress check-inDay 10Understand where they are in process
Decision nudgeDay 14+Move toward decision without pressure

Key insight: The goal of demo follow-up isn't to close immediately. It's to support the buyer's internal process and stay engaged throughout their evaluation.

Proposal Follow-up Sequences

After sending a proposal, the waiting game begins. Your follow-up sequence should balance persistence with patience, providing value while moving toward a decision.

Post-Proposal Follow-up Sequence

Immediate

Same day as proposal sent

Subject Line

Your [Product] proposal

Email Body

Hi [firstName],

As discussed, here's the proposal for [Their Company]: [Proposal link]

Quick summary:

What's included:

  • [Key item 1]
  • [Key item 2]
  • [Key item 3]

Investment: $[amount]/[period]

Timeline: We can start [timeframe] if we move forward by [date].

I've also attached:

  • Detailed scope of work
  • Contract terms overview
  • Customer references

Take your time reviewing. I'll follow up [day] to answer any questions.

[Your Name]

Proposal Follow-up Timing

EmailDayGoal
Proposal delivery0Confirm receipt, set expectations
Check-in3Answer initial questions
Stakeholder support7Help internal process
Competitive positioning10Win the comparison
Decision timeline14Understand status
Negotiation opening18Move to close

Account-Based Marketing Sequences

For high-value target accounts, use a coordinated multi-touch approach that combines email with other channels.

ABM Email Sequence

Campaign start

First touch in ABM campaign

Subject Line

[Their Company] + [Your Company]: Strategic fit?

Email Body

Hi [firstName],

I've been following [Their Company]'s work on [specific initiative]. Impressive progress on [specific detail].

I'm reaching out because we work with companies in [their industry] on [pain point], and based on what I've seen, there might be a strategic fit.

We've helped [Similar Company 1] and [Similar Company 2] with [specific outcomes]. I'd love to explore whether [Their Company] could benefit similarly.

Would you be open to a 20-minute conversation to see if there's alignment?

[Your Name]

P.S. I've put together a brief analysis of [something relevant to their business]. Happy to share regardless of whether we connect.

Measuring B2B Sequence Performance

B2B metrics differ from consumer email because of longer sales cycles and lower volumes.

MetricGood BenchmarkNotes
Open rate35-50%Higher than consumer due to targeted lists
Reply rate (cold)5-15%Focus on positive replies
Meeting booked rate2-8%The metric that matters most
Proposal conversion20-40%After demo or discovery call
Sales cycle lengthTrack trendGoal is to shorten, not just convert

Important: In B2B, a "no" response is actually valuable. It tells you to move on and focus elsewhere. Don't count silence as a negative response.

Tools for B2B Sequences

B2B email sequences need:

  • Multi-touch sequences with conditional logic
  • Integration with CRM to track deal stage
  • Personalization based on company and contact data
  • Team collaboration for coordinated outreach

For SaaS companies selling B2B, Sequenzy handles both marketing automation and transactional emails, with Stripe integration for subscription-based triggers. This is particularly useful if you're running product-led growth alongside outbound sales.

Next Steps

Start with one sequence type:

  1. If you're doing outbound sales: Build the 7-email outreach sequence first
  2. If you have inbound leads: Build the nurture sequence first
  3. If you have demos but low close rates: Build the demo follow-up sequence first

Customize the templates for your product and audience. Test subject lines. Track responses. Iterate based on what works.

For related reading:

The best B2B email sequences don't feel like sequences. They feel like genuine, helpful communication from someone who understands the buyer's challenges. That's the bar you're aiming for.